Research

Publications

*: The authors contributed equally to this work.

1. Chang Su, Jingfei Zhang, Hongyu Zhao. Estimating cell-type-specific gene co-expression networks from bulk gene expression data with an application to Alzheimer’s disease. Journal of the American Statistical Association, forthcoming. [preprint] [code] [R package]

2. Chang Su, Zichun Xu, Xinning Shan, Biao Cai, Hongyu Zhao, Jingfei Zhang. Cell-type-specific co-expression inference from single cell RNA-sequencing data. Nature Communications (2023). [paper] [R package] [Python package]

   1. Selected for talk at Biology of Genomes, Cold Spring Harbor Laboratory, NY, May 2023

   2. Awarded JXTX + CSHL Biology of Genomes scholarship

3. Hussain Bukhari*, Chang Su*, Elvisha Dhamala, Zijin Gu, Keith Jamison, Amy Kuceyeski. Graph‐matching distance between individuals' functional connectomes varies with relatedness, age, and cognitive score. Human Brain Mapping (2023). [paper]

4. Xinyi Zhong*, Chang Su*, Zhou Fan. Empirical Bayes PCA in high dimensions. Journal of the Royal Statistical Society: Series B (Statistical Methodology) (2022). [paper] [software]

Under revision

5. Biqing Zhu, Jae-Min Park, Sarah Coffey, I-Uen Hsu, TuKiet T Lam, Pallavi P Gopal, Stephen D Ginsberg, Jiawei Wang, Chang Su, Hongyu Zhao, David A Hafler, Sreeganga S Chandra, Le Zhang. Single-cell transcriptomic and proteomic analysis of Parkinson’s disease Brains. Under revision at Science Translational Medicine. [preprint]

6. Le Zhang, Chuan Hua He, Sarah Coffey, Dominic Yin, I-Uen Hsu, Chang Su, Yixuan Ye, Chi Zhang, Joshua Spurrier, LaShae Nicholson, Carla V Rothlin, Sourav Ghosh, Pallavi P Gopal, David A Hafler, Hongyu Zhao, Stephen M Strittmatter. Single-cell transcriptomic atlas of Alzheimer’s disease middle temporal gyrus reveals region, cell type and sex specificity of gene expression with novel genetic risk for MERTK in female. Under revision at Nature Communications. [preprint]

7. Biao Cai, Jingfei Zhang, Hongyu Li, Chang Su and Hongyu Zhao. Statistical Inference of cell-type proportions estimated from bulk expression data. [preprint]